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pneumophila , with at least 27 confirmed substrates displaying over 20 distinct enzymatic activities, including lipases, proteases, glycosidases, nucleases, and phosphatases (Rossier et al., 2004

This fungus is consistently enriched in various CLDs (including ALD, MASLD, cirrhosis, and HCC) and is associated with disease severity and poor prognosis, suggesting that targeting this single pathogen could have broad therapeutic effects

doi: 10.1186/s40880-017-0198-3 178 SungJ-YCheongJ-H

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