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At this point it's worth mentioning that HGF over- or miss-expression often correlates with poor prognosis and that the down-regulation of c-Met or HGF expression in human tumor cells reduced their tumorigenicity (Abounader et al., 2002)

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This led to improved muscle regeneration and a 70% increase in the peak torque of injured muscles compared to controls

Nature 393 , 333339 (1998)