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The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88

It means it didn't work well enough as a standalone pharmaceutical drug

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container

Patch test any new product first, and discontinue if you notice irritation

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