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integrifolia leaves, administered at doses up to 5,000 mg/kg, caused no mortality or adverse effects in experimental animals, suggesting that the hydroalcoholic leaf extract is reasonably safe when administered orally to mice

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Orowska, E., Przybyowicz, W., Orlowski, D., Turnau, K

Transcriptomic analyses have revealed changes in gene expression related to ion transport, energy metabolism, and signaling pathways, providing insights into how teleost fish respond to salinity stress