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Description

MSC shows its immunosuppressive effect by directly or indirectly induces the polarization of CD4 + T cells to Tregs, and inhibits the proliferation of B cells and the production of antibodies

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While the majority of patients respond favorably to topical corticosteroids (135), calcineurin inhibitors (136), and immunosuppressants (137), these treatments are often associated with significant adverse effects during long-term use (138)