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FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data

The following reflects anecdotal reports from research forums and is not medical advice

To maintain compound integrity, the peptide is supplied in a stable lyophilized form

Using fine needles or micro-cannulas, the filler is precisely injected into targeted areas to restore volume, smooth wrinkles, and enhance facial contours

JCO.2017.72.773 DOI: 10.1200/JCO.2017.72.7735 Disclaimer: This site is primarily intended for healthcare professionals