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11 , e2307639 (2024)

Firmicutes/Bacteroidetes ( F/B ) ratio, reduce the microbiotas resilience to stress, and promote the elevation of harmful metabolites, thereby inducing systemic inflammation ( Accumulating evidence indicates that bile acids play a crucial role in oral-gut microbiota crosstalk and systemic disease network

ANIMAL ETHICS STATEMENT All animal care and use procedures were approved by the Institutional Animal Care and Use Committee of Jiangsu Agri-animal Husbandry Vocational College (Permit number: jsahvc-202317), and all authors clearly indicated that such guidelines have been followed

Regulators, therefore, treat it differently from medications requiring strict prescriptions

During peroxide detoxification, GSH is oxidized to GSSG and subsequently reduced back to GSH by glutathione-disulfide reductase (GSR, also known as GR) in an NADPH-dependent manner