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These serious side effects are rare, but can occur with Zepbound

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Oral administration of a humid extract of dehydrated leaves is used to treat menorrhagia and diabetes in Australia, and oral administration of an extract of root bark is used to treat fever (9, 88)

In addition, enhanced NO signaling via glyceraldehyde -3- phosphate dehydrogenase (GAPDH) in the brains of AD patients shifts the balance toward tau acetylation, and inhibition of GAPDH-mediated NO signaling can help alleviate A induced cognitive deficits (Sen et al., 2018)