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This pathological condition is characterized by an initial restriction of blood flow to an organ, followed by restoration of perfusion and oxygenation, which paradoxically induces further damage through mechanisms such as oxidative stress and inflammation [1]

Therefore, it is imperative that research be conducted on the mechanism of preeclampsia, which plays a significant role in its prevention and treatment, thereby significantly reducing perinatal adverse outcomes

1983 Mar;49:59-69

SERCA2A, sarcoplasmic endoplasmic calcium ATPase

However, when serine is available, neither restricting exogenous glycine intake nor depleting the endogenous glycine cleavage system can inhibit the proliferation of cancer cells, indicating that nucleotide synthesis and cancer cell growth are supported by serine rather than glycine consumption [171]