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In AML12 cells damaged by excessive APAP, the increase in mitophagy induced by AMSCs co-culture was abolished by DDIT4 knockout, as indicated by increased PINK1, Parkin, and LC3BII with decreased P62 (Fig

inhibits the transfer of melanin to skin cells, visibly reducing dark spots, hyperpigmentation and uneven tone with consistent use

These findings suggest that gut redox homeostasis is a key beneficiary of the restorative processes associated with sleep but that the gut may also actively mediate the systemic effects of sleep, including on longevity and aging (Vaccaro et al., 2020)

J Inorg Biochem 2009

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