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Synaptogenesis, the formation of new synapses, depends heavily on BDNF signaling through the ERK pathway

Kirkland, New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463

Malar DS, Thitilertdecha P, Ruckvongacheep KS et al (2023) Targeting sigma receptors for the treatment of neurodegenerative and neurodevelopmental disorders

Although it was originally characterized as a metastasis suppressor gene, its most well-characterized role is in stimulating the secretion of GnRH from GnRH neurons, in turn leading to gonadotrophin production from pituitary gonadotrophs

Cell Mol Life Sci