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The 17-oestradiol (E2), the predominant form of ovarian oestrogen produced during the early or mid-follicular phase of the human menstrual cycle 42 (analogous to the morning of the proestrus phase in mice), and progesterone (P4), predominantly produced during the luteal phase (analogous to the evening of the proestrus phase in mice) 21,43,44 , are highly lipophilic hormones capable of crossing the bloodbrain barrier (BBB) 45

(A) An antibacterial hydrogel integrating ROS scavenging, O 2 generation and NO release eradicates MRSA infection, relieve inflammation and promotes healing in diabetic wounds

Apolipoprotein E: High-avidity binding to -amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

MEMA contains carotene, vitamin B1, folic acid, folinic acid, isoquercetin, quercetin, tannins, favonoids, and saponins, which act as a good source of natural antioxidants

This unique transformation allows NAC to squelch free radicals directly at the site of ATP energy production, protecting the mitochondrial inner membrane from lipid peroxidation