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Targeting histone modifications Histone modification drugs are capable of rectifying dysregulated histone modification patterns within malignant cells to suppress the aberrant gene transcriptions associated with oncogenesis

A peliminary analysis on behalf of Polish Adult Leukemia Group Jaroslaw Dybko 1 , Agnieszka Piekarska 2 , Donata Urbaniak-Kujda 3 , Monika Biernat 3 , Magdalena Dutka 2 , Alicja Sadowska-Klasa 2 , Sebastian Giebel 4 , Tomasz Wrbel 3 , Kazimierz Kuliczkowski 3 , Lidia Gil 5 1 2 3 3 2 2 4 3 3 5 1 Wroclaw Medical University, Department of Internal and Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw, Poland