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Scientific Communications: imaging 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.06 - IMAGING - Hyperacute O - ESOC25-862 MAPPING DWI SIGNAL REVERSAL AND LONG-TERM TISSUE OUTCOMES FOLLOWING ENDOVASCULAR THERAPY IN ACUTE ISCHEMIC STROKE Thor Hkon Skattr 1,2,3 , Cecilie Mrck Offersen 4,5 , Terje Nome 1 , Kine Bakke 6 , Brian Anthony Enriquez 2 , Jonathan Carlsen 4,5 , Mona Beyer 1,3 , Atle Bjrnerud 6,7 , Anne Hege Aamodt 2,8 1 Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway, 2 Department of Neurology, Oslo University Hospital, Oslo, Norway, 3 Institute of Clinical Medicine, University of Oslo, Oslo, Norway, 4 Department of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 5 Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, 6 Department of Physics and Computational Radiology, Oslo University Hospital, Oslo, Norway, 7 Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway, 8 Department of Neuroscience and Movement Science, The Norwegian University of Science and Technology, Trondheim, Norway Background and Aims: Diffusion-weighted imaging reversal (DWI-R) is commonly observed after efficient reperfusion therapy in acute ischemic stroke

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Nevertheless, astrocytes and other glia can also mediate detrimental effects in neurological disorders either through downregulation of essential functions or through gain of inappropriate functions such as promoting excess inflammation

Therefore, there are still vast opportunities to explore the role of various natural and synthetic compounds in antibiotic potentiation against biofilms

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