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Sakat, S., et al

The primary genetic targets for treating ferroptosis may include p53, Gpx4, ACSL4, and Nrf2

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This multilayered heterogeneity network necessitates that ferroptosis-targeted therapies adopt precise stratification strategies, integrating technologies such as single-cell sequencing and spatial metabolomics to identify sensitive subpopulations and implement targeted interventions

As food is a major resource for folate, studies reported that low folate level due to unbalanced diet is associated with higher prevalence on schizophrenia, particularly in infants with maternal nutritional deficiency 11,93