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Additionally, Minuk and Lewkonia (1986) have even reported familial clustering of Inflammatory Bowel Disease (IBD) and MS, suggesting that they have genetic or environmental risk factors in common

albicans expresses a pore-forming peptide called candidalysin that wreaks havoc on the hosts epithelial cell membranes

Mohammadi S, Kayedpoor P, Karimzadeh-Bardei L, Nabiuni M

On the other hand, another study showed that NRF2 knockdown in human CAR-T cells enhanced anti-tumor immunity in a xenograft murine model implanted with a B-lymphoblastoid cell line, showing that eliminating the antioxidant effect may be beneficial in a lymphoma setting (124)

Maturation skews macrophage polarization from M1 to M2 (interleukin-4 [IL-4], interleukin-10 [IL-10], IL-12, Arginase 1 [Arg-1]