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Besides, HSPB1 was identified as a hub gene in the regulatory network associated with HCC progression and ferroptosis (Fei et al., 2021)

USA 107 , 2261722622 (2010)

This can surpass the antioxidant capacity of cells, causing damage to biomolecules [35].In the absence of universal standards for diagnosing iron toxicity, oxidized phospholipids are often used as indicators [36].Research suggests that polyunsaturated fatty acids (PUFAs) are particularly prone to peroxidation and may contribute to ferroptosis [37]