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It is likely that race-specific and gender-specific differences in bladder tumor biology cooperate to promote the disparities that are observed in bladder cancer

However, isotope-labeled IS are often expensive or unavailable for certain compounds and using a single isotope-labeled IS for multiple structurally diverse compounds is inappropriate due to differences in retention times, matrix effects, ion suppression, fragmentation patterns, and ionization efficiencies

Iron chelators deferoxamine can alleviate ferroptosis and fibrosis in CKD rats (199)

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Consequently, researchers continue to approach the peptide cautiously