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Cushman TR, Gomez D, Kumar R, Likacheva A, Chang JY , Cadena AP, Paris S, Welsh JW

In this chapter, we summarize what has been learned about the mitochondrial biochemical pathways and/or targets of age-related hearing loss (AHL), and examine the link between aging, mitochondrial dysfunction, and hearing loss in rodents and humans

Feng and colleagues [90] reported that acrolein exposure to human lung cells produces a pattern of DNA damage in the p53 tumor suppressor gene which appeared to be similar to the p53 pattern of mutations found in lung cancer