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(Note there is an analogous enzyme in the mitochondria for the urea cycle termed carbamoyl phosphate synthetase I, which also generates carbamoyl phosphate.) Of clinical importance is the intermediate orotate

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doi: 10.1016/j.fitote.2016.05.016, PMID: [DOI] [PubMed] [Google Scholar] Shukla M., Rohatgi S

In collagen, LOX enzymatically catalyzes the reaction of Hyl and lysine residues into reactive aldehyde species, which subsequently spontaneously link to aldehyde species on adjacent molecules (Lucero and Kagan, 2006