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The process of detoxification proceeds in three parts or phases, Phase I, Phase II, and Phase lll

None of these are dose recommendations

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[20,21] A small double-blind trial of a mixture of antioxidants, including 600 mg vitamin E, 1 g vitamin C, and 200 mg NAC taken only during treatment, looked at the potential of this mixture to prevent cardiotoxicity during chemo- and radiotherapy

While EZH2 inhibitors show promise in malignant pleural mesothelioma treatment, their effectiveness is limited by MSC-mediated oncogene activation, suggesting that targeting monocyte recruitment and depleting TAMs may restore the antitumor activity of EZH2 inhibitors [153]