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Conclusions Peptide therapies are increasingly used among musculoskeletal patients, yet high-quality evidence supporting clinical efficacy and perioperative safety remains limited

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For this, wild-type and ZRANB3 knockout U2OS cells transduced with HRASV12 or cyclin E1 retroviral vectors were transfected with control or PRIMPOL siRNA and replication fork progression was monitored by DNA fiber assay 72 h post-transfection