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Skin-related adverse events include rashes, pruritus, and vitiligo

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492 Upon activation, it elicits conformational shifts in the androgen receptor, selectively modulating its interaction with coactivator and corepressor proteins present in various tissues, thereby altering the receptors capacity to modulate gene expression

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Materials and Methods Cell Lines HEK293 cells were obtained from ATTC and maintained in DMEM with 5% fetal bovine serum and Penn/Strep antibiotics and maintained in 5% CO 2