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In most cases, tinnitus is initiated by acquired hearing loss and maintained only when this loss is coupled with distinct neuronal changes in auditory and extra-auditory brain networks

Kasubuchi M, Hasegawa S, Hiramatsu T, Ichimura A, Kimura I

Generally it is believed that PQQ have strongest antioxidant properties which drives these health benefits, but exact underlying cellular or molecular mechanisms are still not fully known (Akagawa et al., 2016a)

8 It also initiates a powerful antioxidant torrent, increasing expression of superoxide dismutase (SOD), glutathione (GSH), catalase, and glutathione peroxidase (GPx)