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Description

It accounts for 75% of deaths associated with cutaneous cancers

Mooijaart, S

Me-DTC may act as an irreversible inhibitor of aldehyde dehydrogenases (ALDH1), whereas the sulfoxide and sulfone metabolites, especially the sulfone metabolite, may be more potent inhibitors of both ALDH 1, and ALDH2

Peak concentrations of the compound are reached after 0.52 h of topical administration

Mice for an immunohistochemistry study were transcardially perfused with phosphate-buffered saline, followed by 10% (v/v) neutral buffered formalin (NBF), with a steady flow rate of 10.0 ml/min using an IPC Digital Peristaltic Pump (Ismatec, Germany)