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In addition, the observed inverse relationship between intracellular sperm levels and average-path velocity (VAP) is important in furthering our understanding of the possible role of free radicals in constraining the actual rate of sperm forward movement within the female reproductive tract, which is vital for successful fertilization

Unapproved New Drug: Any substance that has not completed the formal FDA approval process and fails to qualify for a strict 503A or 503B exemption is classified as an unapproved new drug, the distribution of which is prohibited in interstate commerce

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J Neurosci, 2007