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Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in diet-induced obese mice

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Caspases 3 and 7, key mediators of the mitochondrial apoptotic pathway, were significantly activated by (M+D)/2 after 24 hours in IMR-5/75 -Dox and IMR-32, but not in Be(2)-C and SH-SY5Y/MYCN cells