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As a synthetic analog of growth hormonereleasing hormone (GHRH), Tesamorelin is commonly examined in research for its interaction with GHRH receptors and its downstream influence on endocrine signaling pathways associated with endogenous growth hormone regulation and insulin-like growth factor-1 (IGF-1) activity

And a C18 fatty diacid chain attached at position 26 allows the peptide to bind to albumin in the bloodstream, which slows its clearance and gives it a half-life of approximately seven days