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S767 disrupts intracellular metal homeostasis by depleting iron and elevating copper and zinc

doi: 10.1016/j.coi.2019.11.002 99 BoothbyMRickertRC

It is standard practice in Bayesian trial design methodology 55 to use a community of priors, also known as adversarial priors, whereby an enthusiastic prior is used for futility monitoring while a more skeptical prior is used for the final analysis