mitochondrial glutathione depletion Highly Selective and Prolonged of in Astrocytes Markedly Increases Sensitivity to Peroxynitrite SLC25A39 is necessary for mitochondrial
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells Nature Glutathione and mitochondria Frontiers Novel aggregation induced emission photosensitizers with built in capability of mitochondria targeting and glutathione depletion for efficient photodynamic therapy Nanoscale (RSC Publishing) Mitochondrial Glutathione: Recent Insights and Role in Disease PMC Glutathione Depletion Pathways 1. Precursor Depletion Key bottleneck: Cysteine availability. Source: Diet or hepatic transsulfuration (methionine homocysteine cysteine). Failure mode: Downregulation of cystathionine lyase (CSE) during
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