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Additionally, chrysin exhibited anti-tumor activity against choriocarcinoma cells through modification of mitochondrial membrane potential, disruption of Ca 2+ levels in cytosol, enhancing generation of reactive oxygen species (ROS), and inducing lipid peroxidation, which affects intracellular Ca 2+ homeostasis resulting in cancer cell damage [86]

In the absence of type III receptor, the transforming growth factor (TGF)- type II-B receptor requires the type I receptor to bind TGF-2

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OG also ameliorated non-alcoholic fatty liver disease (NAFLD), as evidenced by reduced hepatic lipid accumulation and normalized adipose tissue metabolism