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Abstract Brain-Derived Neurotrophic Factor (BDNF) is an essential neurotrophin involved in neuronal survival, synaptic plasticity, and neurogenesis, critical for normal brain function as well as the pathology of neurological and psychiatric disorders

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& Brewster, A

Foster LH, Sumar S

Published reviews have concluded that dexrazoxane (Zinecard, an iron-chelating agent), carvedilol (Coreg, a beta-blocker), valsartan (Diovan, an angiotensin receptor blocker), statins (a class of cholesterol-lowering medications), and enalapril (Vasotec, an angiotensin-converting enzyme inhibitor [ACE]-inhibitor), are effective in preventing heart muscle dysfunction and reducing cardiac events in patients treated with anthracyclines (Kalam 2013