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The researchers also found that PPAR was up-regulated and FAO was enhanced in BRAF-mutated melanoma cells after MAPK inhibition therapy, leading to cancer cell resistance [131]

doi: 10.3389/fneur.2019.00218 Received 29 August 2018 Accepted 20 February 2019 Published 19 March 2019 Volume 10 - 2019 Edited by Steven Jacobson, National Institute of Neurological Disorders and Stroke (NINDS), United States Reviewed by Judith Walters, National Institute of Neurological Disorders and Stroke (NINDS), United States

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A calculation was subsequently performed to determine the saturation threshold effect of selenium on hypertension among participants in the medium and highest selenium concentration subgroups