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Although bariatric surgery can lead to weight loss of at least 25% and long-term weight maintenance, it is not scalable at the population level, and many people are still afraid to have surgery because of the possibility of complications, [135, 136]

However, randomized controlled trials of only oral thiamin supplementation have not found any benefit in CHF patients

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From six months to one year of use, the percent of patients who experienced at least 75% of repigmentation on their face increased from 30% to nearly 50%

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