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Moreover, ILDR enhances the efficacy of ICI through microbiota- and BA-mediated mechanisms, including increased DC activation and CD8+ T cell recruitment, potentially driven by DCA enrichment ( Together, these findings suggest that targeting the microbiotaBA axis may improve the efficacy and tolerability of chemoradiotherapy

Capacity Bio has developed CAP-1902, a small-molecule mitophagy booster that functions as an agonist of the Mas-related G-protein coupled receptor (WO2022165189A1), and its effects on the brain, cardiac tissue, liver, and muscles are being investigated

Therefore, a deficiency in L-Glutamine not only starves the gut and immune cells but also severely cripples the body's primary defense mechanism against systemic oxidative damage, creating a vicious cycle of cellular injury and fatigue