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Although the exact mechanism by which -synuclein leads to PD is not completely understood there is evidence that the propensity of this protein to misfold into toxic oligomers promotes disease (reviewed in (El-Agnaf and Irvine 2000

doi: 10.4236/aim.2016.64027 436 Marn-PalmaDTabares-GuevaraJHZapata-CardonaMIFlrez-lvarezLYepesLMRugelesMTet al

The COHbELISA kit (Size 96 Wells, MBS7254040) was used according to the manufacturers instructions on lysates from these cells, allowing sensitive and specific quantification of CO-bound hemoglobin and thereby enabling assessment of CO delivery from the nanoparticles in a cellular environment mimicking erythroid differentiation

2022 Jan 5;27(1):324

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