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If the uptake did not increase after addition of intrinsic factor the B12 malabsorption was likely to be caused by an intestinal condition

C.et al (2004)

(2020) specifically addressed NSAID-induced gut damage a clinically relevant injury model and documented that BPC-157 administration stabilized the claudin-4 and occludin tight junction proteins that are degraded by NSAID exposure, providing a mechanistic explanation for the peptides permeability-protective effects

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