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The heterogeneity of participant recruitment criteria and the lack of control of variables that influence circulating BDNF levels regardless of dementia, such as depressive symptoms, medications, lifestyle, lack of overlap between serum and plasma, and experimental aspects are likely to bias results and prevent study comparability (Balietti et al., 2018)

This change is key for making red blood cells and keeping the nervous system healthy

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This mechanism naturally limits absorption when B12 is consumed in large quantities, with excess amounts typically eliminated through the kidneys without causing harm