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On the other hand, cellular GPx activity level showed a positive correlation with quasi-threshold doses (Dq) and extrapolation numbers but not with general radiosensitivity

Structural analyses reveal tight interactions between L-phosphoserines phosphate group and conserved arginine (Arg42, Arg328) and histidine (His41, His327) residues, suggesting that analogs targeting these residues could yield potent inhibitors (77)

What is now required are more clinical trials to confirm or disprove these preliminary findings together with closer ties between non-clinical and clinical research to forge a link between molecular mechanisms and therapeutic outcomes

El hgado y el rin son los principales rganos involucrados en la sntesis y degradacin de GSH, como as tambin en la circulacin inter-rgano de la cual tambin participan el bazo, los eritrocitos, los leucocitos y el cristalino (7)