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May 10 2021;10(5)doi:10.3390/antiox10050755 Darrow DP

The safest and most effective outcomes occur when therapy is guided by specialists, monitored closely, and combined with healthy lifestyle interventions

LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function

once absorbed and inside the cells it is removed, thus leaving the glutathione molecule intact

The antibody itself must also be optimized: it should bind strongly to the target and internalize efficiently, and it should be engineered (often humanized or fully human) to avoid immune rejection by the patient