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This mode of cell death is closely related to the pathogenesis of various skin pathological conditions, including but not limited to inflammatory skin diseases, autoimmune skin disorders, and skin tumors

doi: 10.1038/s41698-017-0031-0 43 PrezCVSobarzoCMJacoboPVPellizzariEHCigorragaSBDenduchisBet al

Researchers are also cautious about the potential for Mild Fluid Retention or swelling in the extremities, particularly in the course of the initial phases of persistent administration