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W.ClemensJ

Zuckerman et al., 2012)

A transcriptome analysis of copper homeostasis-related genes found a strong elevation in mRNA levels of CTR1 protein encoded by SLC31A1 gene, which was accompanied by an increase in transcript levels for ATP7A, copper metabolism Murr1 domain containing 1, the COX assembly factors, the cupric reductase six transmembrane epithelial antigen of the prostate, and the metal-regulatory transcription factors and specificity protein 1 in colorectal carcinoma samples [31]