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Augmented erythrocyte band-3 phosphorylation in septic mice

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MAPK is a key transmitter of signals from the cell surface to the nucleus and can be activated by factors such as cytokines, hormones, stressors and others to regulate cell growth, differentiation, inflammation and other physiological and pathological processes (92)

Based on their cell marker profiles and cytokine expression, macrophages can be classified into M1 and M2 phenotypes