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doi: 10.1038/s41434-020-0141-0 220 YrigollenCMDavidsonBL

Interestingly, since acetyl-CoA is essential for the acetylation status of chromatin histones 58 , inhibition of acetyl-CoA synthesis as indicated in this study might partly explain the downregulation of our genes of interest in aspirin-treated EG110 yeast cells (Table 1, Fig