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A systematic review of cases of CNS demyelination following COVID-19 vaccination

4.2 Deubiquitinating enzymes and their role in circadian regulation 4.2.1 Deubiquitinating enzymes Deubiquitinases (DUBs) are enzymes that remove ubiquitin moieties from target proteins, reversing the action of E3 ubiquitin ligases and thereby shaping ubiquitin signaling with high accuracy (Srikanta and Cermakian, 2021