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Similarly, in targeted metabolomics studies of urine, previous studies have targeted the abnormalities of reactive oxidative stress, gut bacteria metabolism, 239 amino acid (tyrosine, tryptophan, arginine, proline, methionine, cysteine, and taurine), lipid (phospholipid, sphingolipid, and fatty acid), urea cycle, xenobiotics metabolism, 239 , 240 TCA cycle, and glutamate metabolism 240 in urine of ASD

Most recently, a 52-week phase 2 clinical trial of liraglutide (a GLP-1RA) in PD patients found that liraglutide treatment improves non-motor symptoms, mobility, and quality of life with safety and good tolerance [167]

J Chem Soc Perkin Trans 2:19331935

Therapeutic effects of Biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice