glutathione conjugation of salicylates Phase II Reactions: and Mercapturic Acid Formation in Pharmacokinetics and Pharmacodynamics Glutathione Conjugate - an overview

Nature 388(6642):539547 Hunt R, Xiao S, Megraud F, Leon-Barau R, Bazzoli F, Van der Merwe S, Le Mair A (2011) World Gastroenterology Organization Global Guideline

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Excessive peritoneal iron accumulation leads to overproduction of reactive oxygen species (ROS)-a group of highly reactive chemicals formed from oxygen, which at high concentrations can damage DNA, RNA, proteins, and lipids within the cell (20)-and enhanced activation of nuclear factor kappa-B (NF-B), which, by promoting the expression of matrix metalloproteinases (MMPs), exacerbates inflammation, angiogenesis, and cell adhesion

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