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doi:10.1074/jbc.M110.105601 ^ Allard S.T., Giraud M.F., Naismith J.H

10.1016/s0140-6736(18)30841-9 51 WangH.NaghaviM.AllenC.BarberR

Drp1, dynamin-related protein 1

Notably, the liver PARP activity of patients with severe NAFLD is much greater than that of patients with simple steatosis, suggesting that aberrant PARP-1 activation may contribute to the downregulation of liver PPAR expression in these individuals (115)

Upon analysis of the kin-19 RNAi - dependent metabolic response, treated animals lacked the metabolic plasticity that was observed in wild-type or nhr-49(nr2041) animals