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Paliperidone protects SH-SY5Y cells against MK-801-induced neuronal damage through inhibition of Ca(2+) influx and regulation of SIRT1/miR-134 signal pathway

Tumor-targeted anti-VEGF RNAi capable of sequentially responding to intracellular microenvironments for potent systemic tumor suppression

Anuria and hematuria are additional associated renal complications (192)

Despite its acceptable safety profile, nilotinib demonstrated limited clinical benefit in PD patients, likely due to its poor brain penetration and insufficient cerebrospinal fluid concentrations to achieve meaningful c-Abl inhibition

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