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Together, it can be concluded that intracellular selenium status (hydrogen selenide) regulates the expressions of seleno-GPxs primarily at the translation level by controlling the stability of their mRNAs as well as by facilitating the biosynthesis and subsequent incorporation of Sec into the peptide sequence (Fig

Representative images showing axon degeneration (red arrows) and gliosis (yellow*) are present in p-phenylenediamine (PPD) stained optic nerves from control and ALA treated DBA mice

In wet AMD, an excess of VEGF leads to formation of new, unhealthy blood vessels

Cancer Res 65(7):2890-2898, 2005

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